TWO people were seriously hurt in a crash on the A303 when a red Renault Megane ended up on its roof.
Police are now appealing for witnesses to the incident yesterday.
Officers went to the A303 westbound between Solstice Park and Countess roundabout at about 12.40pm on Wednesday.
A 54-year-old man, who was driving the car, suffered a serious back injury and was taken to Salisbury District Hospital.
A female passenger, 79, sustained serious back and pelvic injuries and was taken to Southampton Hospital.
Two other occupants of the vehicle, one thought to be a child, were taken to Salisbury District Hospital to be treated for shock and minor injuries.
The road was closed while emergency services including Wiltshire Air Ambulance were at the scene, although all patients were transported by South Western Ambulance Service.
Police say the Renault was travelling west towards Amesbury when it collided with the central barrier before returning to the carriageway and ending up on its roof on the verge.
“We would like to hear from anyone who may have seen the vehicle prior to the collision, or anyone who may have witnessed the collision and has not already spoken to police,” said a Wiltshire Police spokesman.
Police can be called on 101 or Crimestoppers anonymously on 0800 555 111.
Highways England said that the road was reopened shortly before 3.40pm yesterday.